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Pineal, chicken

Specimen from a chicken. Distribution of CD3+ and CD4+ cells. Pineal-associated lymphoid tissue (PALT) stained with anti-CD3 (panel A) and anti-CD4 (panel B). Note that the majority of the lymphocytes are double positive for CD3 and CD4 (yellow in Panel D). Several CD3+/CD4- cells are seen primarily along the periphery of the PALT and bordering a pineal follicle (arrows, Panel D). The DIC image (Panel C) shows the border of the PALT (white dashed line).

Image courtesy of Mosenson and McNulty BMC Immunology 2006 7:1 doi:10.1186/1471-2172-7-1

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