Spleen, dog (labels) - histology slide

This is a histology slide of a dog spleen. The area of white pulp where T cells are located is readily seen. This area consists of numerous T cells forming a kind of sheath around the central artery; it is called the periarterial lymphoid sheath or PALS. Note the plasma cell located in the germinal center of the lymphoid follicle; plasma cells arise from B cells and make specific antibodies.

Histology slide courtesy of OSU College of Veterinary Medicine. Copyright © Charlotte L. Ownby. Reprinted with permission.